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Dudman Lab

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More in this Lab Landing Page
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Lab Updates

10/17/16 | New paper describing a reagent born from a collaborative (Karpova, Looger, Hantman, Ritola) + visitor project (Schaffer @ Berkeley): directed evolution of a retrograde AAV
08/31/16 | A thoughtful commentary on the clinical implications of Yttri & Dudman 2016 appeared in Movement Disorders
06/01/16 | Eric Yttri's new paper describing flexible, learned control of movement in the basal ganglia is published in Nature
03/28/16 | Our new collaborative review with BLAM lab is now available at Current Opinion.
09/10/15 | Our first paper studying the role of dopamine in movement using a mouse model of Parkinson’s disease is online now at Cell.
07/23/15 | Wei-Xing's paper about inferring dopamine neuron activity from evoked potentials is online with an informative commentary in F1000.
03/28/16 | Please consider applying to our meeting on Action Selection at Janelia this Fall.
01/01/15 | A faithful, but changing, code for space along the dorsoventral axis of the hippocampus. Paper with our collaborator Isabel Muzzio is now out online.
04/15/15 | The fourth edition of The Rat Nervous System with a chapter on the Basal Ganglia by Chip Gerfen and Joshua Dudman is now available.
04/01/15 | Scientifica has now licensed RIVETS; expect improved hardware integration with some of the best equipment out there.
02/10/15 | Learn about our lab's connections to the local science magnet school - the Loudoun Academy of Science.
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About the lab
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The work in our lab aims to elucidate the neurobiology of purposive behavior, as well as its pathological disruption in Parkinson's disease and addiction. See all the updates from the lab.

Our lab spans a wide range of technical approaches from electrophysiology during behavior to two-photon imaging. For our work we seek talented people with skills in physiology, behavior, imaging, or, computation, and a strong desire to combine multiple technical approaches. Inquiries can be sent directly to the lab by contacting us.

For interested students, we have a small number of slots for exceptional graduate students through the Janelia Graduate Program or the Graduate Research Fellowship program. For undergraduates, our lab is a regular participant in the Janelia Undergraduate Scholars program.


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Published work

Over the past few years we have focused on studying the circuits of the basal ganglia in the context of reward seeking behaviors in mice. Previous work has spanned a range of techniques and questions from behavioral measures of disease progression in human patients to the atomic structure of glutamate receptors.

Data derived from: Google Scholar.


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"...The problem of actions, in other words the effect which the organism is striving to achieve, is something which is not yet, but which is due to be brought about. The problem of action, thus, is the reflection or model of future requirements (somehow coded in the brain); and a vitally useful or significant action cannot be either programmed or accomplished if the brain has not created a prerequisite directive in the form of future requirements that we have just mentioned."

-N. Bernstein (1962)